Formal total synthesis of (+)-trehazolin. Application of an asymmetric aldol-olefin metathesis approach to the synthesis of functionalized cyclopentenes.
نویسندگان
چکیده
An asymmetric synthesis of the aminocyclopentitol pseudosugar of trehazolin has been completed. The synthesis hinges on an asymmetric aldol-ring closing metathesis strategy to construct the five-membered ring with control of both the relative and absolute stereochemistry.
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 66 11 شماره
صفحات -
تاریخ انتشار 2001